Genes, Minds, Machines

My personal Substack

Discover, build, transform… and the effort to dismantle it.

Making sense of the science of public health

I'm increasingly certain no one knows anything about anything. Previous founder @ SOOT. Before that was googling. Writes about programming, AI, startups, Civ, and misc other things.

Analysis and discussion covering epidemiology, statistics and science communication from the author of 'The Rules of Contagion' and 'The Perfect Bet'. New book 'Proof' available now: proof.kucharski.io

Technology, education, and human flourishing. All through the lens of a prototyping mindset.

Natural philosophy, belles-lettres, polemics.

A newsletter about statistics as a way of seeing the world—not just numbers, but critical thinking, discernment, and structured sensemaking.