AI

Protein language models are bad at mutational effect prediction

Biology is hard. Yes, even for AI.

Mar 19 • Claus Wilke

Sociopathic AI agents

AI alignment will likely require creating AIs with genuine empathy

Feb 15 • Claus Wilke

LLMs excel at programming—how can they be so bad at it?

My explanation for the mystery of why LLMs can be both exceptionally good and quite terrible at programming.

Nov 6, 2025 • Claus Wilke

We still can’t predict much of anything in biology

Biology is hard. Yes, even for AI.

Oct 7, 2025 • Claus Wilke

Teaching data visualization in the time of generative AI

If students want to cheat with AI, the least I can do is make them own up to it.

Sep 12, 2025 • Claus Wilke

Are AI papers now written by AI?

Are AI papers now written by AI?

Aug 12, 2025 • Claus Wilke

"I asked the AI" is not research

You can't reliably fact-check or research obscure topics by asking an AI. It may know less about the topic than you do.

Aug 2, 2025 • Claus Wilke

Limitations of protein language models applied to viral data

Biology is hard. Yes, even for AI.

Jul 23, 2025 • Claus Wilke

No, AlphaFold has not completely solved protein folding

Biology is hard. Yes, even for AI.

Jul 12, 2025 • Claus Wilke

PhD-level intelligence or the graduate student from hell

AI companies love to tout that their models are approaching—or have reached—PhD-level intelligence. This is blatant nonsensical marketing geared towards…

Jul 9, 2025 • Claus Wilke

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